Southwest Houston Vacations from $220

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Your Southwest Houston Vacation

Make organizing your next big adventure simple with a Southwest Houston vacation package. Whether it's the cuisine, history or something else entirely that brings you to this destination, our packages will help you discover the best of it. Trying to decide where to go on your trip to Southwest Houston? Alief is a top city you won't want to miss. From the moment you book your Southwest Houston vacation to when you return home, Expedia will be with you each step of the way.

The Latest Southwest Houston vacation packages

Price found within the past 48 hours. Click for updated prices.
Hyatt Place Houston-North
Hyatt Regency Houston/Galleria
Moody Gardens Hotel, Spa and Convention Center
The Lancaster Hotel
Holiday Inn Express & Suites Houston NW/Beltway 8 West Road by IHG
Don't see what you're looking for?
See all available trips from San Antonio to Southwest Houston
View all trips

Where to stay in Southwest Houston

Find the best Southwest Houston areas and neighborhoods for the activities you enjoy most. Learn more about Southwest Houston

Discover the most popular places to visit in Southwest Houston

What to do in Southwest Houston

Southwest Houston Hotel Deals

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd, Houston, TX
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $127 total per night from Sep 11 to Sep 12
$127 total
Sep 11 - Sep 12
Total includes taxes and fees
8/10 Very Good! (2,353 reviews)
"Good hotel. Beautiful. Bad : Parking. Everything to do with it. Inconvenient and wat"

Reviewed on Aug 9, 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $106 total per night from Sep 7 to Sep 8
$106 total
Sep 7 - Sep 8
Total includes taxes and fees
8.2/10 Very Good! (1,506 reviews)
"We loved the convenience of the location and the shuttle service, but the elevators were in disrepair and they only had one, which created a delay. The pool needed service while we were there but we called the lobby and that was quickly corrected. There were no ice machines on the guest floors. This ..."

Reviewed on Aug 8, 2025

Hilton Houston Plaza/Medical Center
Blossom Hotel Houston

Blossom Hotel Houston

4 out of 5
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $169 total per night from Sep 1 to Sep 2
$169 total
Sep 1 - Sep 2
Total includes taxes and fees
9/10 Wonderful! (3,467 reviews)
"POOR FOOD OPTIONS, LIMITED MENU AND FLAVOR WAS NOT GOOD. REGARDING CUSTOMER SERVICE, VERY LIMITED AND THEY DID NOT HONOR EXPEDIA LEVEL OR ANYTHING."

Reviewed on Aug 11, 2025

Blossom Hotel Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.